Potential of mesenchymal stem cell-derived exosomes in the treatment of androgenetic alopecia

Citations

WEB OF SCIENCE

5
Citations

SCOPUS

5

초록

Exosomes are derived from various cell types, including mesenchymal stem cells (MSCs), and play a crucial role in cellular communication, significantly influencing tissue repair and regeneration and facilitating the healing process. Thus, insights into the functions of exosomes present novel opportunities in regenerative therapy. This article aims to discuss the promising potential of exosomes derived from human adipose-derived MSCs in treating androgenetic alopecia. This study aims to highlight how exosomes derived from human adipose-derived MSCs enhance dermal papilla cell proliferation through the Wnt/beta-catenin pathway, counteracting the effects of excessive dihydrotestosterone and offering a novel approach for treating androgenetic alopecia.

키워드

Exosome; Mesenchymal stem cells; Hair regrowth; Dermal papilla cell; Wnt/beta-catenin
제목
Potential of mesenchymal stem cell-derived exosomes in the treatment of androgenetic alopecia
저자
Rajendran, Ramya Lakshmi; Ahn, Byeong-Cheol; Gangadaran, Prakash
DOI
10.4252/wjsc.v17.i5.107078
발행일
2025-05-26
유형
Letter
저널명
WORLD JOURNAL OF STEM CELLS
권
17
호
5
페이지
1 ~ 4