Secondary healing property using Neoveil®, a polyglycolic acid bioabsorbable sheet on the oral mucosal defects

초록

Neoveil (R) is a wound surface-covering agent composed of polyglycolic acid(PGA) effective for secondary heal-ing. This study evaluated the secondary healing property of oral cavity mucosal defects using the PGA sheet. Thirty-four patients who underwent surgical excision of oral benign and malignant lesions, precancerous lesions, and tumors were evaluated. The PGA sheet was placed over the open wound to aid secondary heal-ing. The defects were reviewed post-operatively for secondary healing, contracture, and secondary defor-mity. Male to female ratio was 20:14, and the mean age was 63.5 years. In all cases, the oral mucosal defect was present after the wide excision of the mucosal lesion. The PGA sheet was used as a surface covering agent which was found to be effective in secondary healing of the wound. Any side effects and adverse reac-tions which were caused by the PGA sheet was not evident. It can be used to avoid skin graft or free flap reconstruction or deformity from the direct closure in moderate size oral mucosal defect.(c) 2022 Published by Elsevier Masson SAS.

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