The Effective Way of Botulinum Toxin Injection to Reduce Bite Force: Preliminary Study

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초록

This study investigated bite force changes after botulinum toxin type A (BoNT-A) injection into different masticatory muscles. Thirty-five male participants were divided into three groups: masseter only (M), masseter and temporalis (MT), and masseter, temporalis, and medial pterygoid (MTP). Bite force was measured before and up to 6 months after injection with the Dental Prescale II system. Baseline values showed no significant group differences. Group M exhibited significant reduction at 1 and 2 weeks, with recovery within 1 month. Group MT showed a similar transient decrease, also recovering after 1 month. In contrast, Group MTP demonstrated a more pronounced and prolonged reduction, persisting up to 4 months before recovery. These results indicate that the extent and duration of BoNT-A effects depend on the number of muscles injected. Multi-muscle injections, including the medial pterygoid, provide more durable suppression. However, further research involving patient populations is needed to clarify whether multi-muscle injection strategies provide therapeutic benefits in clinical conditions such as temporomandibular disorders or oromandibular dystonia.

키워드

bite force; botulinum toxin; masticatory muscles; medial pterygoid muscles; MASTICATORY PERFORMANCE; MUSCLE; BRUXISM; TEMPORALIS; OCCLUSION; DYSTONIA; EFFICACY; SAFETY
제목
The Effective Way of Botulinum Toxin Injection to Reduce Bite Force: Preliminary Study
저자
Kang, Kun-Hwa; Jung, Jae-Kwang; Byun, Jin-Seok; Kim, Ji Rak
DOI
10.3390/toxins17100519
발행일
2025-10-21
유형
Article
저널명
Toxins
권
17
호
10