Improvement of chiral separation efficiency through temperature control during one time high performance liquid chromatography analysis

Citations

SCOPUS

7

초록

This study examined how manual temperature control affects the separation of two enantiomers of five racemic mixtures using high-performance liquid chromatography (HPLC) in terms of separation factor (α), resolution (Rs), and the number of theoretical plates (N). The results showed that heating/cooling during one time HPLC analysis improved the separation factor and resolution. © 2022 Wiley Periodicals LLC.

키워드

chiral separation; HPLC; one time analysis; separation efficiency; temperature control
제목
Improvement of chiral separation efficiency through temperature control during one time high performance liquid chromatography analysis
저자
Eun, Danbi; Jeong, Young-han; Ryoo, Jeongjeong
DOI
10.1002/chir.23444
발행일
2022
유형
Article
저널명
Chirality
권
34
호
7
페이지
941 ~ 947