레이저 소결 적층 시스템을 이용한 3차원 수산화인회석인공지지체 제작에 관한 연구

초록

Calcium-phosphate-based bioceramics are promising biomaterials for scaffolds because they can assist in boneregeneration. In this study, a laser sintering deposition system was developed, and 3D hydroxyapatite (HA)scaffolds were fabricated. The main process conditions of the HA scaffolds were laser power, table velocity, andlaser focal distance. As the laser power increased, the line width, line height, and layer thickness also increased. Further, the line width, line height, and layer thickness decreased as the table velocity increased. As the laserfocal distance increased, the line width increased, but the line height and layer thickness decreased. Thefabricated green scaffolds were sintered at 1050 °C and 1150 °C. The sintered scaffolds had a uniform andcontinuous interconnected shape, with pore sizes ranging from 850 to 950 ㎛ having 53% porosity. Thecompressive strength of the scaffolds decreased from 0.72 MPa (1050 °C) to 0.53 MPa (1150 °C). Thebiocompatibility of the scaffolds was investigated by analyzing the adhesion of osteoblast-like MG-63 cellscultured on the surfaces of the scaffolds. The results indicate that the scaffold sintered at 1050 °C had goodmechanical and biological properties compared to that at 1150 °C

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