Systems biology and multiomics integration in biological treatment of textile wastewater

초록

With advances in life sciences, multiomics technologies (genomics, transcriptomics, proteomics, and metabolomics) are becoming increasingly popular. The catabolic potential of microorganisms is remarkable because they have genes, enzymes, and pathways to degrade organic compounds. The high toxicity and durability of textile dyes, as well as their limited biodegradability, cause serious environmental impacts. Bioremediation is the most advantageous and effective way to degrade textile dyes using microbes. Advanced multiomics approaches are successfully used to characterize microorganisms that degrade textile dyes, novel enzymes and genes, and the responsible metabolic pathways involved in biotransformation. The genetic diversity of microorganisms and community structures can be determined using sophisticated and efficient multiomics technologies. Through the use of advanced molecular techniques, complex bacterial communities can be characterized in detail with respect to their structural and functional aspects, and questions related to their biodegradation potential can be addressed. Multiomics approaches have already been successfully used to characterize microorganisms that degrade textile dyes in contaminated environments. Considering that metabolites are downstream products of many genes, transcripts, and protein interactions, metabolomics could help in the integration of these multiomics datasets. This book chapter describes recent advances and omics approaches that have been used to determine the molecular mechanisms of textile dye degradation. © 2023 Elsevier Inc. All rights reserved.

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