Antimicrobial activity of Penicillium species metabolites

초록

Secondary metabolites produced by bacteria and fungi are important reservoirs of compounds that can be used in the development of drugs to benefit human health. Fungi are capable of producing a wide variety of secondary metabolites during their cellular development. These secondary metabolites include antibiotics, alkaloids, fatty acids, alcohols, ketones, and poisons. The genus Penicillium, which is comprised of various types of fungi, is a possible source of bioactive chemicals. These metabolites are produced from antibacterial penicillins, echinocandins, which are effective against fungi, cholesterol-lowering statins, and cyclosporins, which inhibit the immune system. Penicillium is a diverse genus of fungi that includes over 300 species that have been described. These species can be found all over the world on a variety of substrates, such as soil and food, and in a variety of ways, ranging from necrotrophic pathogenicity to endophytic mutualism. The potential secondary metabolites that can be produced by the Penicillium fungus are outlined in this chapter's summary. Because these fungi host such a diverse collection of microorganisms, there is a tremendous amount of potential for the development of bioactive scaffolds. © 2024 Elsevier Inc. All rights reserved.

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