Generalized correlation for predicting the droplet size in a microfluidic flow-focusing device under the effect of surfactant

  • Minh Duc Nguyen; 
  • Khac Vu Tran; 
  • Cu Trung Dang; 
  • Kim, Gyu Man; 
  • Trung Dung Dang; 
  • 외 2명
Citations

WEB OF SCIENCE

11
Citations

SCOPUS

11

초록

This paper describes an investigation on the dynamic behavior of droplet formation in a microfluidic flow-focusing device (MFFD) under the effect of surfactant using a phase-field method and the Koterweg stress applied in Navier-Stokes equations. The effects of variously important parameters, such as capillary number (Ca-0), water fraction (wf), the viscosity ratio (alpha), and particularly surfactant concentration (c(b)), were examined. Consequently, the numerical results match the experimental ones. Additionally, the droplet formation is significantly affected by the surfactant, and the droplet size decreases with increasing c(b) for the whole range of both wf and Ca-0. Based on the extensive study, the phase diagrams with two main modes, namely, dropping and threading, are provided. A mountain shape of the dropping mode was found, and this mode can be extended for higher wf with the presence of surfactant. In particular, new generalized correlations as a function of wf, Ca-0, and c(b) are first proposed for predicting quickly and effectively the droplet size. Furthermore, the droplet formation depends significantly on alpha. With the presence of surfactant, smaller size of the droplet forms and the threading mode occurs at very high alpha. The results obtained in this study are very useful for understanding the dynamic behavior of droplet formation in MFFDs, which can be used in potential applications such as biomedical and drug delivery systems. Published under an exclusive license by AIP Publishing.

키워드

MICROPARTICLES; EMULSIONS; MECHANISM
제목
Generalized correlation for predicting the droplet size in a microfluidic flow-focusing device under the effect of surfactant
저자
Minh Duc Nguyen; Khac Vu Tran; Cu Trung Dang; Kim, Gyu Man; Trung Dung Dang; Hong Duc Ta; Ich Long Ngo
DOI
10.1063/5.0084872
발행일
2022-03
유형
Article
저널명
Physics of Fluids
권
34
호
3