Microencapsulation of pluripotent stem cell-derived pancreatic and liver cells: biological needs and technological solutions

초록

Pluripotent stem cell-derived products are versatile tools for studying disease and developing cellular therapies. Microencapsulation technologies offer solutions for scalability, prolonged survival, and transplantability of these stem-cell derived products. This review describes current methods and materials utilized for stem cell encapsulation. Specifically, the differentiation of stem cell-derived beta cells and hepatocytes is explored. This includes the current state of differentiation protocols, examples of microencapsulation for differentiation and transplantation, and future directions.

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