An Update on the Effectiveness of Probiotics in the Prevention and Treatment of Cancer

  • Sankarapandian, Vidya; 
  • Venmathi Maran, Balu Alagar; 
  • Rajendran, Ramya Lakshmi; 
  • Jogalekar, Manasi P.; 
  • Gurunagarajan, Sridharan; 
  • ... Ahn, Byeong-Cheol; 
  • 외 2명
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초록

Probiotics are living microbes that play a significant role in protecting the host in various ways. Gut microbiota is one of the key players in maintaining homeostasis. Cancer is considered one of the most significant causes of death worldwide. Although cancer treatment has received much attention in recent years, the number of people suffering from neoplastic syndrome continues to increase. Despite notable improvements in the field of cancer therapy, tackling cancer has been challenging due to the multiple properties of cancer cells and their ability to evade the immune system. Probiotics alter the immunological and cellular responses by enhancing the epithelial barrier and stimulating the production of anti-inflammatory, antioxidant, and anticarcinogenic compounds, thereby reducing cancer burden and growth. The present review focuses on the various mechanisms underlying the role of probiotics in the prevention and treatment of cancer.

키워드

probiotics; immunomodulation; metastasis; biotherapy; oncogene kinase; LACTIC-ACID BACTERIA; ANTIMUTAGENIC ACTIVITIES; LACTOCOCCUS-LACTIS; DOWN-REGULATION; CULTURED MILK; IN-VIVO; LACTOBACILLUS; NISIN; ANTICANCER; APOPTOSIS
제목
An Update on the Effectiveness of Probiotics in the Prevention and Treatment of Cancer
저자
Sankarapandian, Vidya; Venmathi Maran, Balu Alagar; Rajendran, Ramya Lakshmi; Jogalekar, Manasi P.; Gurunagarajan, Sridharan; Krishnamoorthy, Rajapandiyan; Gangadaran, Prakash; Ahn, Byeong-Cheol
DOI
10.3390/life12010059
발행일
2022-01
유형
Article
저널명
Life
권
12
호
1