Recommendations for the Use of Next-Generation Sequencing and the Molecular Tumor Board for Patients with Advanced Cancer: A Report from KSMO and KCSG Precision Medicine Networking Group

  • Yoon, Shinkyo; 
  • Kim, Miso; 
  • Hong, Yong Sang; 
  • Kim, Han Sang; 
  • Kim, Seung Tae; 
  • 외 19명
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초록

Next-generation sequencing (NGS) is becoming essential in the fields of precision oncology. With implementation of NGS in daily clinic, the needs for continued education, facilitated interpretation of NGS results and optimal treatment delivery based on NGS results have been addressed. Molecular tumor board (MTB) is multidisciplinary approach to keep pace with the growing knowledge of complex molecular alterations in patients with advanced solid cancer. Although guidelines for NGS use and MTB have been developed in western countries, there is limitation for reflection of Korea's public health environment and daily clinical practice. These recommendations provide a critical guidance from NGS panel testing to final treatment decision based on MTB discussion.

키워드

Key words Next -generation sequencing; Molecular tumor board; Advanced solid cancer; Precision medicine; Genomic alterations; DEAMINATION; DIAGNOSIS; PANELS
제목
Recommendations for the Use of Next-Generation Sequencing and the Molecular Tumor Board for Patients with Advanced Cancer: A Report from KSMO and KCSG Precision Medicine Networking Group
저자
Yoon, Shinkyo; Kim, Miso; Hong, Yong Sang; Kim, Han Sang; Kim, Seung Tae; Kim, Jihun; Yun, Hongseok; Yoo, Changhoon; Ahn, Hee Kyung; Kim, Hyo Song; Lee, In Hee; Kim, In-Ho; Park, Inkeun; Jeong, Jae Ho; Cheon, Jaekyung; Kim, Jin Won; Yun, Jina; Lim, Sun Min; Cha, Yongjun; Jang, Se Jin; Zang, Dae Young; Kim, Tae Won; Kang, Jin Hyoung; Kim, Jee Hyun
DOI
10.4143/crt.2021.1115
발행일
2022-01
유형
Article
저널명
Cancer Research and Treatment
권
54
호
1
페이지
1 ~ 9