Biogenic-mediated silver nanoparticles using heneicosane and their enhanced antimicrobial, antiproliferative, sensing capability and photocatalytic potential

초록

Latest changes in nanotechnology have given a lot of attention to eco-friendly procedures that promote economic sustainability using conservative interaction settings and non-toxic precursors. As a reducing and stabilizing agent, an aqueous extract of heneicosane was used in the current work to create bio-augmented silver nanoparticles utilizing an easy, creative, and reasonably priced green approach. The produced Ag NPs were analyzed using a variety of techniques, including UV–Vis, XRD, FT-IR, FE-SEM with EDAX, and TEM. An agar well technique was used to evaluate the antimicrobial properties of bio-mediated Ag NPs against pathogenic organisms. To test the anti-proliferative activity, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT assay) and neutral red absorption (NRU) assays, which can detect hydrogen peroxide and photocatalytic analysis of methylene red dye, were performed. The Ag NPs showed powerful antimicrobial activity against a variety of microbial pathogens and substantial anticancer activity in human lung cancer cells (A549). Interestingly, the highest methylene red degradation percentage obtained was 96.2 after 55 min. As a result, the selected nanoparticles mixture enhanced antibacterial, anticancer, sensing, and photocatalytic capabilities. The combination might be a beneficial tool for eliminating dye pollution from wastewater and, ideally, for fighting lung cancer in the pharmaceutical industry. © 2023, King Abdulaziz City for Science and Technology.

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