Synthesis of Tricyclic Tetrazoles by Cascade Diazotization/ Intramolecular Radical C-H Heteroarylation of Arenes

초록

A cascade diazotization/intramolecular radical CH heteroarylation of 1-benzyloxy- 5-aminotetrazoles and 1phenethyl-5-aminotetrazoles as substrates using sodium nitrite and acetic acid without any heating, catalysis, irradiation, or electrolysis is reported. This one-pot reaction afforded the desired tricyclic tetrazole products in good yields (up to 94%) without isolation of the diazonium salt intermediate under mild reaction conditions.

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