Comparative response area of cadaveric tympanic membrane using Doppler optical coherence tomography

초록

Doppler optical coherence tomography (DOCT) is a non-destructive imaging technique designed to measure the movement of a sample by applying the Doppler effect to optical coherence tomography (OCT) signal data. It was designed to acquire a tomography image of the tympanic membrane (TM) and a calculated Doppler signal in real time with OCT using the CUDA parallel processing algorithm while inducing vibration of the TM with an audio signal. Afterwards, the thickness of the TM inside the ROI was measured using software, and the degree of response was analyzed according to the thickness. To measure the tomographic thickness of the TM responding to sound waves, image processing was used to acquire the upper and lower boundaries of the TM. To reduce the error in thickness measurement according to the angle of the TM, the shortest distance between the upper and lower boundaries at each pixel was used to reduce the error in the thickness measurement. In addition, by mapping the thickness information to a two-dimensional array, the movement of the TM in response to sound waves was finally analyzed through a histogram according to the thickness of the TM. Finally, we were able to obtain the tendency of the response according to the thickness of the TM, and quantitatively analyze the change in the reactivity according to the area of the TM. © 2023 SPIE

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