TiO2 Nanoparticles Derived from Capparis Zeylanica: An Effective Treatment for Diabetic and Food Borne Infections

초록

The current work is concerned with the fabrication of titanium dioxide (TiO2) nanoparticles (NPs) employing Capparis zeylanica leaf extract, as well as the investigation of the antidiabetic potential of the synthesized nanoparticles in relation to food-borne infections. Various spectroscopic and microscopic approaches were used to characterize the biosynthesized TiO2 NPs. Synthesized TiO2 NPs were tested for their antimicrobial activity against various microbial pathogens using the agar well diffusion technique and demonstrated effective growth inhibition. Furthermore, the dyslipidemia status of alloxan-induced diabetic rats supplemented TiO2 NPs significantly improved. It also reduced blood glucose levels and revealed substantial changes in the liver and pancreatic profiles over the days. Therefore, the synthesized TiO2 NPs showed potential antidiabetic and antimicrobial potential, indicating a good alternative for environmental and biological applications.

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